Medline ® Abstracts for References 5,11,60,71
of 'Chronic functional constipation and fecal incontinence in infants and children: Treatment'
Consultation with the specialist: encopresis: assessment and management.
Schonwald A, Rappaport L
Pediatr Rev. 2004;25(8):278.
Developmental Medicine Center, Boston Children's Hospital, MA, USA.
Diagnosis and management in children with severe and protracted constipation and obstipation.
DAVIDSON M, KUGLER MM, BAUER CH
J Pediatr. 1963;62:261.
Croffie JMB, Fitzgerald JF. Idiopathic constipation. In: Pediatric Gastrointestinal Disease, 4th, Walker WA, Goulet O, Kleinman RE, et al (Eds), BC Decker Inc., Ontario 2004. p.1001.
no abstract available
Serum beta-carotene, retinol, and alpha-tocopherol levels during mineral oil therapy for constipation.
Clark JH, Russell GJ, Fitzgerald JF, Nagamori KE
Am J Dis Child. 1987;141(11):1210.
Twenty-five children with chronic constipation underwent serial monitoring of serum beta-carotene, retinol (vitamin A1), and alpha-tocopherol (vitamin E) levels during mineral oil therapy. Mineral oil was administered between meals. Patients were monitored for up to four months of therapy. Mean serum beta-carotene levels fell from 1.0 +/- 0.5 mumol/L (55.7 +/- 26.0 micrograms/dL) to 0.7 +/- 0.4 mumol/L (35.9 +/- 22.1 micrograms/dL) after the first month of mineral oil therapy and remained depressed throughout the remainder of the study. Serum alpha-tocopherol levels remained unchanged throughout the observation period. There was a modest increase in serum retinol levels during the study, especially after three months (from 1.48 +/- 0.84 mumol/L [42.3 +/- 24.1 micrograms/dL]to 2.22 +/- 0.77 mumol/L [63.5 +/- 22.1 micrograms/dL]). We conclude that while a short course of mineral oil can induce a reduction in the serum level of beta-carotene, the treatment has no adverse effect on serum levels of retinol and alpha-tocopherol.
Department of Pediatrics, James Whitcomb Riley Hospital for Children, Indianapolis.