Chordoma and chondrosarcoma of the skull base
- Carl Snyderman, MD, MBA
Carl Snyderman, MD, MBA
- Professor, Departments of Otolaryngology and Neurological Surgery
- University of Pittsburgh School of Medicine
- Section Editors
- Jay S Loeffler, MD
Jay S Loeffler, MD
- Section Editor — Neurooncology
- Professor of Radiation Oncology
- Harvard Medical School
- Patrick Y Wen, MD
Patrick Y Wen, MD
- Section Editor — Neurooncology
- Professor of Neurology
- Harvard Medical School
- Marvin P Fried, MD, FACS
Marvin P Fried, MD, FACS
- Section Editor — Head and Neck Surgery
- Professor and University Chairman, Department of Otorhinolaryngology - Head and Neck Surgery
- Montefiore Medical Center, Albert Einstein College of Medicine
The anatomic junction of the neural and facial viscerocranium is termed the skull base (figure 1A-B). This area is critically important because it supports the brain and allows all the neurovascular structures to either enter or exit the skull.
Neoplasms may originate within the skull base or involve it by growth from either the dura or extracranial structures. Skull base tumors include a number of different histologic cell types.
Chordoma and chondrosarcoma arising in the skull base will be reviewed here. Topics discussed elsewhere include:
●Chordomas arising in the sacrum or elsewhere along the spinal cord (see "Spinal cord tumors").
●Chondrosarcomas at sites other than the skull base (see "Chondrosarcoma").
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- CLINICAL PRESENTATION
- Signs and symptoms
- Imaging studies
- Differential diagnosis
- Radiation therapy
- - Charged particle RT
- - Photon techniques
- Advanced disease
- - Chondrosarcoma
- - Chordoma
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS