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Chordoma and chondrosarcoma of the skull base

Carl Snyderman, MD, MBA
Section Editors
Jay S Loeffler, MD
Patrick Y Wen, MD
Marvin P Fried, MD, FACS
Deputy Editor
April F Eichler, MD, MPH


The anatomic junction of the neural and facial viscerocranium is termed the skull base (figure 1A-B). This area is critically important because it supports the brain and allows all the neurovascular structures to either enter or exit the skull.

Neoplasms may originate within the skull base or involve it by growth from either the dura or extracranial structures. Skull base tumors include a number of different histologic cell types.

Chordoma and chondrosarcoma arising in the skull base will be reviewed here. Topics discussed elsewhere include:

Chordomas arising in the sacrum or elsewhere along the spinal cord (see "Spinal cord tumors").

Chondrosarcomas at sites other than the skull base (see "Chondrosarcoma").

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Literature review current through: Dec 2017. | This topic last updated: Nov 27, 2017.
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