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Choice of drug therapy in primary (essential) hypertension

Johannes FE Mann, MD
Section Editors
George L Bakris, MD
Norman M Kaplan, MD
Deputy Editor
John P Forman, MD, MSc


There is no uniform agreement as to which antihypertensive drugs should be given for initial therapy. The major options are:

Thiazide-type diuretics

Angiotensin-converting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs)

Calcium channel blockers

Beta blockers, which are now rarely used for initial therapy in the absence of a specific indication for their use


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Literature review current through: Apr 2017. | This topic last updated: Mar 30, 2017.
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