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Cervical cytology: Evaluation of high-grade squamous intraepithelial lesions (HSIL)

Authors
Annekathryn Goodman, MD
Warner K Huh, MD
Section Editor
Barbara Goff, MD
Deputy Editor
Sandy J Falk, MD, FACOG

INTRODUCTION

Cervical cytology became the standard screening test for cancer of the uterine cervix and premalignant cervical lesions with the introduction of the Papanicolaou (Pap) smear in 1941 [1]. The incorporation of human papillomavirus testing to cervical cancer screening strategies has improved detection of cervical neoplasia and allowed further risk stratification.

Cervical cytology findings may be reported as atypical squamous cells (ASC), low-grade squamous intraepithelial lesions (LSIL), high-grade squamous intraepithelial lesions (HSIL), or atypical glandular cells (AGC).

Evaluation of women with cervical cytology with HSIL is reviewed here. Cervical cancer screening strategies and techniques, interpretation of cervical cytology results, follow-up of other abnormal cytology results, and management of cervical neoplasia are discussed separately:

(See "Screening for cervical cancer".)

(See "Cervical cancer screening tests: Techniques for cervical cytology and human papillomavirus testing".)

              

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Literature review current through: Nov 2016. | This topic last updated: Mon Jan 18 00:00:00 GMT+00:00 2016.
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