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Cellular mechanisms of diastolic dysfunction

Author
James P Morgan, MD, PhD
Section Editor
Wilson S Colucci, MD
Deputy Editor
Susan B Yeon, MD, JD, FACC

INTRODUCTION

Approximately one-third of patients with symptomatic congestive heart failure have a normal ejection fraction and symptoms that are entirely or in large measure a result of diastolic dysfunction. Diastolic dysfunction is caused by one or more of the following abnormalities in cardiac structure:

Hypertrophy

Fibrosis

Infiltrative diseases

Pericardial constriction

                         

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Literature review current through: Nov 2016. | This topic last updated: Fri May 22 00:00:00 GMT+00:00 2015.
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References
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