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Causes of pulmonary eosinophilia

Authors
Amy D Klion, MD
Peter F Weller, MD, FACP
Section Editor
Bruce S Bochner, MD
Deputy Editor
Helen Hollingsworth, MD

INTRODUCTION

Eosinophilic lung diseases are a heterogeneous group of disorders that share the feature of abnormally increased numbers of eosinophils within the pulmonary airways and parenchyma [1,2]. The defining characteristics needed for the diagnosis of pulmonary eosinophilia include [3-5]:

Peripheral blood eosinophilia with abnormalities on pulmonary imaging studies

Lung tissue eosinophilia demonstrated in transbronchial or open lung biopsies

Increased eosinophils in bronchoalveolar lavage (BAL) fluid (eg, >10 percent)

Peripheral blood eosinophils are, by no means, uniformly increased in all types of eosinophilic lung diseases [6,7], and conventional chest radiographs may fail to detect lung parenchymal disease [8].

                       

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Literature review current through: Nov 2016. | This topic last updated: Thu Feb 25 00:00:00 GMT 2016.
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