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Abnormal uterine bleeding in adolescents: Management

Nirupama K De Silva, MD
Section Editors
Amy B Middleman, MD, MPH, MS Ed
Mitchell Geffner, MD
Deputy Editor
Mary M Torchia, MD


Menstrual disorders and abnormal uterine bleeding (AUB) are among the most frequent gynecologic complaints in adolescents. AUB refers to bleeding that is excessive or occurs outside of normal cyclic menstruation [1]. AUB is described by a variety of terms and may be caused by a number of genital and nongenital tract diseases, systemic disorders, and medications (table 1). (See "Abnormal uterine bleeding in adolescents: Differential diagnosis and approach".)

Anovulatory uterine bleeding is the primary cause of AUB in adolescents and generally resolves with maturation of the hypothalamic-pituitary-ovarian axis.

The management of abnormal uterine bleeding in otherwise healthy adolescents is the focus of this topic review. The management of AUB in adolescents who have chronic disease, underlying coagulation disorders, or are undergoing chemotherapy, solid organ, or hematopoietic stem cell transplantation is beyond the scope of this topic review. Such patients should be managed in conjunction with the appropriate subspecialist. As an example, (see "Heavy or irregular uterine bleeding during chemotherapy").

The evaluation of AUB in adolescents and the evaluation and management of causes of AUB other than anovulatory uterine bleeding in premenopausal women are discussed separately:

(See "Abnormal uterine bleeding in adolescents: Definition and evaluation".)


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Literature review current through: Oct 2015. | This topic last updated: Oct 12, 2015.
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