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Bronchopulmonary sequestration

Christopher M Oermann, MD
Section Editors
Gregory Redding, MD
Leonard E Weisman, MD
Deputy Editor
Alison G Hoppin, MD


Bronchopulmonary sequestration (BPS), sometimes referred to simply as pulmonary sequestration, is a rare congenital abnormality of the lower airway. It consists of a nonfunctioning mass of lung tissue that lacks normal communication with the tracheobronchial tree and that receives its arterial blood supply from the systemic circulation [1].

BPS can present in several ways. Extralobar BPS are often identified on prenatal ultrasound and become symptomatic early in life, whereas intralobar BPS are more commonly identified later in life secondary to recurrent infection.

The postnatal presentation and management of BPS will be discussed below. Prenatal manifestations and management are described in a separate topic review. (See "Prenatal diagnosis and management of bronchopulmonary sequestration".)


BPS is a nonfunctioning mass of lung tissue, with airway and alveolar elements, that lacks normal communication with the tracheobronchial tree, and that receives its arterial blood supply from the systemic circulation. The subtypes are classified anatomically, as follows:

Intralobar sequestration (ILS) – An intralobar pulmonary sequestration (ILS, also known as intrapulmonary sequestration), is located within a normal lobe and lacks its own visceral pleura. ILS accounts for about 75 percent of BPS.

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Literature review current through: Nov 2017. | This topic last updated: Nov 29, 2017.
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