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Tahaniyat Lalani, MBBS, MHS
John C Murray, MD
Section Editor
Daniel J Sexton, MD
Deputy Editor
Elinor L Baron, MD, DTMH


Botryomycosis is a chronic suppurative infection characterized by a granulomatous inflammatory response to bacterial pathogens; it may present with cutaneous or, less commonly, visceral involvement [1]. Botryomycosis was first described in a horse in 1870 by a German pathologist. The name "botryomycosis" was coined in 1884, but its bacterial nature was not discovered until 1919 [2]. The term "botryomycosis" is derived from the Greek word "botrys" (meaning "bunch of grapes") and "mycosis" (a misnomer, due to the presumed fungal etiology in early descriptions). Other terms used to describe botryomycosis include bacterial pseudomycosis, staphylococcal actinophytosis, granular bacteriosis, and actinobacillosis.


Botryomycosis is a relatively uncommon disease, and its description is limited to case reports in children and adults. It occurs more commonly among immunocompromised patients, although infection in immunocompetent patients has also been described [3]. The specific role of the host immune response is not fully understood [4-6].

Risk factors associated with botryomycosis include [4,5,7-11]:


Diabetes mellitus

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Literature review current through: Nov 2017. | This topic last updated: Aug 21, 2017.
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