History, molecular mechanisms, and endoscopic treatment of Barrett's esophagus

Gastroenterology. 2010 Mar;138(3):854-69. doi: 10.1053/j.gastro.2010.01.002. Epub 2010 Jan 18.

Abstract

This report is an adjunct to the American Gastroenterological Association Institute's medical position statement and technical review on the management of Barrett's esophagus, which will be published in the near future. Those documents will consider a number of broad questions on the diagnosis, clinical features, and management of patients with Barrett's esophagus, and the reader is referred to the technical review for an in-depth discussion of those topics. In this report, we review historical, molecular, and endoscopic therapeutic aspects of Barrett's esophagus that are of interest to clinicians and researchers.

Publication types

  • Historical Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Barrett Esophagus / etiology
  • Barrett Esophagus / history
  • Barrett Esophagus / pathology
  • Barrett Esophagus / therapy*
  • Cell Transformation, Neoplastic / pathology
  • Esophageal Neoplasms / history
  • Esophageal Neoplasms / pathology
  • Esophageal Neoplasms / therapy*
  • Esophagoscopy* / history
  • Esophagoscopy* / methods
  • Esophagus / pathology*
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Metaplasia
  • Precancerous Conditions / etiology
  • Precancerous Conditions / history
  • Precancerous Conditions / pathology
  • Precancerous Conditions / therapy*
  • Risk Factors
  • Treatment Outcome