Medline ® Abstract for Reference 29
of 'Bacterial vaginosis'
Variability of bacterial vaginosis over 6- to 12-month intervals.
Ness RB, Kip KE, Soper DE, Stamm CA, Rice P, Richter HE
Sex Transm Dis. 2006;33(6):381.
OBJECTIVES: To examine variability in bacterial vaginosis (BV) over 6- to 12-month intervals.
STUDY DESIGN: One thousand one hundred ninety-three women were followed for a median of 3 years with serial vaginal swab Gram stains for BV. Discrete time hazard models were fit to identify independent risk factors for BV.
RESULTS: Women with BV at study entry were categorized as having normal flora at the next visit 20% of the time, and women with normal flora at study entry were categorized as having BV at the next visit 20% of the time. Among women with initially normal flora, factors associated with BV were black race, lower education, a history of BV, a history of chlamydial/gonococcal cervicitis, and lack of monogamy.
CONCLUSION: About one fifth of women with normal flora develop BV over a given 6- to 12-month interval, and the modifiable risk factors of cervicitis and lack of monogamy contribute to the development of BV.
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