Medline ® Abstract for Reference 111
of 'Bacterial vaginosis'
Comparison of tinidazole given as a single dose and on 2 consecutive days for the treatment of nonspecific bacterial vaginosis.
Ekgren J, Norling BK, Degre M, Midtvedt T
Gynecol Obstet Invest. 1988;26(4):313.
Nonspecific bacterial vaginosis, defined as the presence of clue cells, was treated in a randomized, double-blind study with (1) tinidazole 2 g as a single dose (82 patients), (2) tinidazole 2 g on 2 consecutive days (84 patients), and (3) with placebo (81 patients). The cure rates, both clue cells and Gardnerella vaginalis absent, were 51, 74 and 4%, respectively. A closer clinical and microbiological evaluation showed the 2-day regimen to be superior.
Møllergaten spesiallegesenter, Oslo, Norway.