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Medline ® Abstract for Reference 23

of 'Atypical fibroxanthoma'

Combined intraepithelial squamous neoplasia and atypical fibroxanthoma of the cornea and limbus.
Engelbrecht NE, Ford JG, White WL, Yeatts RP
Am J Ophthalmol. 2000 Jan;129(1):94-6.
PURPOSE: To investigate a case of an unusual neoplasm of the cornea and limbus.
METHODS: A 59-year-old man presented with a highly vascularized, nodular mass involving the left cornea and limbus. An excisional biopsy and, subsequently, a superficial lamellar keratectomy and multiple conjunctival biopsies were performed. At the 6-month follow-up examination, repeat conjunctival biopsies were performed.
RESULTS: Histopathologic examination of the corneal specimen showed a high-grade intraepithelial squamous neoplasia (in situ carcinoma) overlying an atypical fibroxanthoma.
CONCLUSION: We report the clinical and histologic appearance of a corneal/limbal neoplasm consisting of an intraepithelial squamous neoplasia and an atypical fibroxanthoma.
Department of Ophthalmology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.