Medline ® Abstract for Reference 23
of 'Approach to the patient with abnormal liver biochemical and function tests'
Hepatitis E: source and route of infection, clinical manifestations and new developments.
Scobie L, Dalton HR
J Viral Hepat. 2013 Jan;20(1):1-11.
Hepatitis E was previously thought to be a disease of developing countries causing significant morbidity and mortality in young adults, particularly among pregnant women and patients with pre-existing chronic liver disease. Recent studies have shown that hepatitis E is also an issue in developed countries. In this setting, hepatitis E is a zoonotic infection and causes acute infection mainly in middle-aged and elderly men; and chronic infection in the immunosuppressed. The scope and burden of disease are still emerging. The diagnosis of hepatitis E should be considered in any patient with hepatitis, irrespective of their age or travel history.
Glasgow Caledonian University, Glasgow, UK.