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Approach to the adult patient with a bleeding diathesis

Reed E Drews, MD
Section Editor
Lawrence LK Leung, MD
Deputy Editor
Jennifer S Tirnauer, MD


Bleeding that is spontaneous, excessive, or delayed in onset following tissue injury results from a localized pathologic process or a disorder of the hemostatic process, involving a complex interplay among vascular integrity, platelet number and function, coagulation factors, and fibrinolysis. This topic review will discuss the diagnostic approach to the patient with abnormal bleeding.

Congenital and acquired disorders of platelet function, as well as the hemostatic process and associated disorders, are discussed separately.

(See "Overview of hemostasis".)

(See "Approach to the adult with unexplained thrombocytopenia".)

(See "Congenital and acquired disorders of platelet function".)

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Literature review current through: Nov 2017. | This topic last updated: Jan 11, 2017.
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