Medline ® Abstract for Reference 12
of 'Antithrombotic therapy for prosthetic heart valves: Indications'
12
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Comparison of efficacy, safety, and cost of low-molecular-weight heparin with continuous-infusion unfractionated heparin for initiation of anticoagulation after mechanical prosthetic valve implantation.
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Fanikos J, Tsilimingras K, Kucher N, Rosen AB, Hieblinger MD, Goldhaber SZ
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Am J Cardiol. 2004;93(2):247.
We compared the efficacy, safety, and impact on postoperative hospital length of stay and inpatient hospital costs of low-molecular-weight heparin with that of unfractionated heparin as a "bridge" to achieving therapeutic levels of anticoagulation with warfarin in patients with newly implanted prosthetic heart valves. The patients who received low-molecular-weight heparin had a shorter length of stay and decreased postoperative costs compared with the control subjects receiving unfractionated heparin.
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Cardiovascular Division, the Department of Pharmacy, and Center for Clinical Excellence, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
PMID