Lovenox (enoxaparin sodium) therapy appears to be safe and efficacious for pregnant women who are candidates for either prophylactic or therapeutic heparin. However, the use of enoxaparin and other low-molecular-weight heparins for therapeutic anticoagulation is not recommended for pregnant women with prosthetic heart valves. Additionally, enoxaparin should be used with caution or discontinued before administration of epidural for pain relief during labor.