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Medline ® Abstract for Reference 49

of 'Androgenetic alopecia in men: Pathogenesis, clinical features, and diagnosis'

49
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Early androgenetic alopecia as a marker of insulin resistance.
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Matilainen V, Koskela P, Keinänen-Kiukaanniemi S
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Lancet. 2000;356(9236):1165.
 
The previously proven association between androgenetic, alopecia and serious cardiovascular events raises a question of the common pathogenetic mechanism of these disorders. Our practice-based case-control study in men aged 19-50 years showed a strikingly increased risk of hyperinsulinaemia and insulin-resistance-associated disorders such as obesity, hypertension, and dyslipidemia in men with early onset of alopecia (<35), compared with age-matched controls. This finding supports the hypothesis that early androgenetic alopecia could be a clinical marker of insulin resistance.
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PMID