Medline ® Abstract for Reference 49
of 'Androgenetic alopecia in men: Pathogenesis, clinical features, and diagnosis'
Early androgenetic alopecia as a marker of insulin resistance.
Matilainen V, Koskela P, Keinänen-Kiukaanniemi S
The previously proven association between androgenetic, alopecia and serious cardiovascular events raises a question of the common pathogenetic mechanism of these disorders. Our practice-based case-control study in men aged 19-50 years showed a strikingly increased risk of hyperinsulinaemia and insulin-resistance-associated disorders such as obesity, hypertension, and dyslipidemia in men with early onset of alopecia (<35), compared with age-matched controls. This finding supports the hypothesis that early androgenetic alopecia could be a clinical marker of insulin resistance.