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Medline ® Abstracts for References 84-86

of 'Anaphylaxis: Emergency treatment'

84
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Anaphylaxis and anesthesia: controversies and new insights.
AU
Dewachter P, Mouton-Faivre C, Emala CW
SO
Anesthesiology. 2009;111(5):1141.
 
AD
Service d'Anesthésie-Réanimation&Service d'Aide Médicale Urgente (SAMU) de Paris, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, UniversitéParis-Descartes, France. pascale.dewachter@nck.aphp.fr
PMID
85
TI
The level of evidence 5 blues: investigating medicine when experience trumps equipoise.
AU
Puttgen HA, Mirski MA
SO
Crit Care Med. 2013 Jan;41(1):359-61.
 
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PMID
86
TI
Methylene Blue: Magic Bullet for Vasoplegia?
AU
Hosseinian L, Weiner M, Levin MA, Fischer GW
SO
Anesth Analg. 2016 Jan;122(1):194-201.
 
Methylene blue (MB) has received much attention in the perioperative and critical care literature because of its ability to antagonize the profound vasodilation seen in distributive (also referred to as vasodilatory or vasoplegic) shock states. This review will discuss the pharmacologic properties of MB and review the critical care, liver transplantation, and cardiac anesthesia literature with respect to the efficacy and safety of MB for the treatment of shock. Although improved blood pressure has consistently been demonstrated with the use of MB in small trials and case reports, better oxygen delivery or decreased mortality with MB use has not been demonstrated. Large randomized controlled trials are still necessary to identify the role of MB in hemodynamic resuscitation of the critically ill.
AD
From the *Department of Anesthesiology, and†Department of Cardiothoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
PMID