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Medline ® Abstract for Reference 77

of 'Alcoholic cardiomyopathy'

Cirrhotic cardiomyopathy.
Zardi EM, Abbate A, Zardi DM, Dobrina A, Margiotta D, Van Tassell BW, Van Tassel BW, Afeltra A, Sanyal AJ
J Am Coll Cardiol. 2010;56(7):539.
Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction, and 7% to 21% of deaths after orthotopic liver transplantation result from overt heart failure. In this review, we critically evaluate the existing literature on the pathophysiology and clinical implications of cirrhotic cardiomyopathy.
Department of Clinical Medicine, University Campus Bio-Medico, Via Alvaro del Portillo, Rome, Italy. e.zardi@unicampus.it