Official reprint from UpToDate®
www.uptodate.com ©2017 UpToDate, Inc. and/or its affiliates. All Rights Reserved.

Medline ® Abstract for Reference 72

of 'Alcoholic cardiomyopathy'

Left Ventricular Strain and Rotation by 2-D Speckle Tracking Echocardiography Identify Early Alcoholic Cardiomyopathy.
Wang Y, Li G, Sun Y, Shan G, Xu R, Guo L
Ultrasound Med Biol. 2016 Aug;42(8):1741-9. Epub 2016 May 5.
This study assessed whether 2-D speckle tracking echocardiography (STE) derived from left ventricular (LV) strain and rotation is capable of detecting LV dysfunction associated with alcoholic cardiomyopathy. Ninety-two male chronic alcoholic patients were grouped by alcohol intake amount and duration: mild (n = 30;>90 mg ethanol daily, 3-5 d per wk for 5-8 y); moderate (n = 30;>90-150 mg ethanol daily, 3-5 d per wk for 9-20 y); and severe (n = 32;>150 mg ethanol daily, 6-7 d per wk for>10 y). Thirty non-drinkers were recruited as healthy controls. Rotation and twist values were lower in the severe group compared with the other groups (p < 0.05). The moderate and severe alcohol groups demonstrated lower longitudinal, circumferential and radial strain values and early to late filling (E/A) ratios compared with the mild group and non-drinkers (all p < 0.05). 2-D STE-derived strain and rotation are reliable echocardiographic markers for detecting left ventricular dysfunction in patients at risk of developing alcoholic cardiomyopathy.
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.