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Adjuvant radiation therapy for high-grade gliomas

Authors
Helen A Shih, MD
Tracy Batchelor, MD, MPH
Section Editors
Jay S Loeffler, MD
Patrick Y Wen, MD
Deputy Editor
April F Eichler, MD, MPH

INTRODUCTION

High-grade gliomas are malignant, often rapidly progressive brain tumors that are divided into anaplastic gliomas (anaplastic astrocytoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma) and glioblastoma (GBM) based upon their histopathologic features [1]. (See "Classification and pathologic diagnosis of gliomas".)

Most high-grade gliomas are best managed with a combined modality approach, incorporating adjuvant postoperative radiation therapy (RT) and adjuvant chemotherapy following initial surgery. Postoperative RT is discussed in this topic.

Other patient management topics that are covered separately include:

The diagnostic approach to patients with suspected brain tumors (see "Clinical presentation and diagnosis of brain tumors")

Initial surgical management of high-grade gliomas (see "Clinical manifestations and initial surgical approach to patients with high-grade gliomas")

                 

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Literature review current through: Nov 2016. | This topic last updated: Wed Jul 22 00:00:00 GMT+00:00 2015.
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