Acute kidney injury (AKI), formerly referred to as acute renal failure (ARF), is defined as an abrupt reduction in kidney function measured by a rapid decline in glomerular filtration rate. AKI is an important contributing factor to the morbidity and mortality of critically ill neonates.
AKI results in the disturbance of the following renal physiological functions:
●Impairment of nitrogenous waste product excretion
●Loss of water and electrolyte regulation
●Loss of acid-base regulation